Nematode Pheromones
Nothing clarifies your value proposition like one hundred customer interviews.
To our surprise, neither conventional nor organic growers of specialty and row crops were satisfied with the current pest management tools. Regardless of their pest control practices, conventional, organic, or integrated pest management (IPM), growers are looking for new solutions to persistent pest problems. Keep reading.
It’s incredible how much the insight from one hundred interviews can focus your market entry strategy and position your startup for success.
Pheronym develops pheromone products from microscopic roundworms, nematodes to control agricultural pests. By controlling nematode behavior, we can control both pest nematodes and insects. Our goal at the 6-week NSF I-corps team program was to identify the beachhead market for our product entry.
The first week we interviewed Land O Lakes. We were shocked to learn the number of acres infested with soybean cyst nematode, a microscopic roundworm that parasitizes plant roots and reduces yield. We learned that farmers need eco-friendly solutions for soybean cyst nematode, and seed treatments are an excellent solution. We immediately realized that seed treatment was our ultimate market. However, it requires a long time to get to market. Just the field trails need 2-3 years for the channel partners to conduct. Luckily, the second week, we identified our beachhead market, Keep reading.
News release by Janice López-Muñoz
WASHINGTON, DC, September, 22, 2020—In a successful return-to-space mission, research study results indicate that beneficial insect-killing nematodes (small round worms) can be used in the future for natural control of insect pests when humans are growing crops in space. The research objective was to study entomopathogenic (insect-killing) nematodes (EPNs) foraging and infection dynamics in space onboard the International Space Station (ISS) between December 2019 and January 2020.
These beneficial roundworms may have “what it takes” for controlling pest insects that threaten crops grown aboard during long-term human missions in space. That’s the implication of findings from experiments conducted aboard the ISS and published in the journal npj|Microgravity.
This EPNs space mission research was a collaborative effort led by Dr. Fatma Kaplan, CEO of Pheronym, an award-winning ag-biotech pest management company that enables sustainable farming through its novel platform of nematode pheromones, the Center for the Advancement of Science in Space (manager of the International Space Station U.S. National Laboratory) and USDA-ARS (Agricultural Research Service) co-project director research leader Dr. David Shapiro-Ilan. The research was sponsored by the ISS National Lab, who partners with NASA to utilize the U.S. research allocation aboard the orbiting laboratory. Keep Reading
This news release is featured by https://www.newsbreak.com/news/2068007935467/space-nematodes-a-giant-leap-for-interplanetary-agriculture
https://phys.org/news/2020-09-space-nematodes-giant-interplanetary-agriculture.html
By Luke Dormehl
The parasitic space worms are coming, and they’re ready to kill.
Without proper pest control, farmers on Earth risk losing up to 80 percent of their crops. Needless to say, that kind of bad harvest could prove devastating for a developing space colony. Clearly, some form of pest control is sensible to investigate. Since air quality is critical in space (being a limited resource, and it not being quite so easy to open a window to get clean air), it would also make sense if pest control methods were biological, non-toxic ones. Keep Reading
Pheronym is developing pheromones from microscopic roundworms, nematodes, to control agricultural pests; nematodes, and insects. Our end users are growers, conventional and organic farmers. Our task was very simple: “Talk to 100 growers to understand their pain points with respect to difficult pests”. Traditionally, at I-corps participants get out of the building or go to conferences to meet people for in-person interviews. We could easily go to a few grower conferences and a couple of industry conferences and maybe meet 20- 25 people at each conference. How hard could it be talking to 100 growers? Keep reading!
When: November 12, 2020
Where: National Steinbeck Center/Virtual
Time: 4-6pm PT/ 7-9pm EST
From Farms to Incubators: Women Innovators in California Agtech
Dr. Fatma Kaplan’s story will be featured in the women innovators in California Agtech exhibition at the Steinbeck Center. The photos and works are in the actual gallery and will be available online and in-person.
Food and agriculture receive well-deserved attention, especially during the pandemic–the World Food Program recently won the Nobel Prize.
Book is available at Barnes & Noble
From Farms to Incubators: Women Innovators in California Agtech by Amy Wu
See the following link for the table of content or pre-order.
It is a great honor to be among the Women Innovators of California Agtech. See chapter twelve for Dr. Fatma Kaplan.
Dr. Kaplan is presenting our breakthrough technology on nematode pheromones to provide eco-friendly sustainable pest control solutions at SynBioBeta, the Global Synthetic Biology Conference, Sep 29 – Oct 1, 2020..
Come and join us for the Startup Bio Draft at SynBioBeta on Sep 29, 2020!
Nematode Pheromone Extract Dramatically Increases Efficacy of Nematode Dispersal for Crop Biocontrol
DAVIS, California – August 24, 2020– Pheronym, an Ag-biotech pest control company, has been granted its patent for its breakthrough in creating a way to increase the effectiveness of Nematodes’ ability to control pest insects, naturally, in agriculture. The patent is listed as “Nematode dispersant composition and method” and is US patent number: US 10,736,326 B2.”
While nematodes (microscopic roundworms) are regularly used in pest control, commercially available nematodes do not disperse as well as they could when they are applied to a field. This is because they have lost their pheromone signal to hunt for new prey. Since the insect target is mobile, the nematodes need to be actively moving and hunting for a new insect host. Pheronym’s patent directly impacts this problem – significantly improving the mobility and aggressiveness of the nematodes making them more effective in killing pests. It also expands their effective temperature range.
“It’s great to have additional validation on our breakthrough,” said Dr. Fatma Kaplan, CEO of Pheronym. “The recognition of our IP along with four peer-reviewed studies on its effectiveness bring us another step closer to broad commercialization of this natural approach to pest control that will be better for people and our planet. ”
DAVIS, CA, UNITED STATES, August 10, 2020 — Pheronym, an ag-biotech pest control company, announced today the results of their fourth peer-reviewed study, this one focused on the results of their collaboration with the Center for the Advancement of Science in Space (manager of the International Space Station U.S. National Laboratory) and USDA-ARS during onboard experiments conducted on the International Space Station (ISS) between December 2019 and January 2020. The study, published in Nature Partner Journal/npj Microgravity, highlights that nematodes successfully emerged from consumed insect host cadavers, moved through soil, found and infected bait-insects in a manner equivalent to Earth controls. However, nematodes that developed entirely in space, from the egg stage, died upon return to Earth, unlike controls in microgravity and on Earth.
The research, led by Dr. Fatma Kaplan, focused on the beneficial nematodes’ dispersal, foraging, infectivity, and pheromone production in microgravity.
“This agricultural biocontrol experiment in space gives insight to long-term space flight for symbiotic organisms, parasite biology, and the potential for sustainable crop protection in space,” said Dr. Fatma Kaplan, CEO of Pheronym. “It gives us valuable insight on how to keep beneficial nematodes alive and viable for agriculture on other planets.”
We are honored that our technical milestones were selected as Research Highlights in the past two years by the Society of Invertebrate Pathology (SIP), Division of Nematodes.
2020 Research highlight by the SIP Division of Nematodes
The results of the peer-reviewed work are published in Scientific Reports by the Nature publishing group.
2019 Research highlight by the SIP Division of Nematodes
The results of the efficacy trials were peer-reviewed and published in the Journal of Invertebrate Pathology.